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Document Type |
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Article In Journal |
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Document Title |
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THE A NTJOXIDA NT DEFENCE STA TUS IN FA SCIOL4 HEPA TICA AND SCHISTOSOMA MANSONI infection مضادات الاكسدة في حالات الاصابة الكبدية بالفاسيولا والشستومامانسوني |
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Subject |
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THE A NTJOXIDA NT DEFENCE STA TUS IN FA SCIOL4 HEPA TICA AND SCHISTOSOMA MANSONI infection |
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Document Language |
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English |
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Abstract |
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Medical and surgical problems especially in tropical and subtropical areas arise frequently from helminthic invasion affecting the liver and/or biliary tract. The antioxidant enzymes have a potential role in evasion of the oxidative burst killing mechanisms by the immune cells. The aime of the study was to evaluate the influence on hepatobiliary system posed by Fasciola hepatica with or without S.mansoni co-infection respective to the antioxidant status, total bile acids, liver function tests, ultrasonography and endoscopic examination. Thirty subjects infected with Fasciola hepatica (mean age 38.93±4.6) were categorized into those with S.mansoni infection (GI) or without (Gil) compared to thirty age matched subjects free of Fasciola hepatica but with S.mansoni infection (Gill) or its absence represented as controls (G IV). Ultrasonography, computed tomography (CT), magnetic resonance insonnation (MR1), and endoscopic retrograde cholangeo-pancreatography (ERCP) are used for diagnosis of early and late stages of F.hepatica and antifasciola antibody titer. Biochemical assessments of the antioxidant defense status by measuring serum level of enzymatic activities of superoxide dismutase, catalase, and total giutathione peroxidase, and vitamins A, C, and E were done as well as total serum bile acids and liver function tests. Results exhibited reduced levels of superoxide dismutase (SOD), catalase and glutathione peroxidase oxidase as well as the antioxidant vitamins A, C, E in G1>GII>GIII>G1V and they were statistically significant P |
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ISSN |
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1110-0133 |
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Journal Name |
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journal of the medical research institute |
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Volume |
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23 |
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Issue Number |
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3 |
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Publishing Year |
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1423 AH
2002 AD |
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Article Type |
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Article |
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Added Date |
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Sunday, February 17, 2013 |
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Researchers
| خالد عمر ابو النجا | abalnaja, khaled omer | Researcher | Doctorate | kabualnaja@kau.edu.com |
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