Document Details

Document Type : Article In Journal 
Document Title :
Histological and ultrastructural studies on the impact of antioxidants against the toxicity of certain heavy metals in the ovarian chicken
دراسة نسيجية وحول تأثير المواد المضادة للاكسدة ضد سمية المعادن الثقيلة في بعض الدجاج المبيض
 
Subject : Histological and ultrastructural studies on the impact of antioxidants against the toxicity of certain heavy metals in the ovarian chicken 
Document Language : English 
Abstract : The objective of this study was designed to determine the effects of mixture of two heavy metals (Lead and cadmium) as lead and cadmium acetate (0.17 mg / 1 and 0.06 mg / I) respectively on the ovarian structure of the adult Lohaman chickens. Also, the possible ameliorative impacts of 250 mg/kg of diet, vitamin C and 200 mg/kg of diet vitamin E. separately and in combination as antioxidants in treating the heavy metal toxicity. The chicks were classified into 6 groups. The light and ultra structural microscopic studies showed marked histopathological changes in the lead and cadmium-treated groups (GII, Gill, and GIV) in comparison with G I, GV and GVI. These changes were represented by increase in number of the growing ova presence of edematous and fibrotic areas in the interstitial tissue, undifferentiating of the cal layer, degeneration of the cal glands and vacuolization of the follicular cells. The administration of vitamin C alone with lead and cadmium diet (GIII), improved the constituents of the ooplasmic organelles which were represented by great numbers of elongated and healthy mitochondria and scattered transosomes. However the administration of vitamin E alone with lead and cadmium diet (GIV), improved the cell membranes of many cells and their membranous structures such as RER and mitochondria either in the cal or follicular cells and the fibers become more obvious. The combination of vitamins C and E in diet containing lead and cadmium (GV) were more effective than the addition of each of them alone in preventing the degeneration of the theca layer and follicular cells and improvement of different ovarian structures such as the appearance of well developed vitelline membrane and zone radiate. Moreover, both vitamins accelerate the maturation of follicles and improve the general ovarian structures. This study proved that the administration of a combined dose of vitamins C and E with the daily diets and drinking water in the poultry farms especially those near to the sites of pollution of the sewage and industrial wastes, is highly recommended. 
ISSN : 1687-4870 
Journal Name : African Journal of Biotechnology 
Volume : 3 
Issue Number : 3 
Publishing Year : 1427 AH
2007 AD 
Article Type : Article 
Added Date : Monday, February 28, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
اسامة ابوزنادةabu zenadh, osama ResearcherDoctorate 

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