Document Details

Document Type : Article In Journal 
Document Title :
Asymmertic aldol reactions of an N-propionyl dervative of chiral auxiliary derived from terpene alcohol cis- myrtanol with benzaldehyed
ردود فعل الدول أسيميرتيك لديرفاتيف إن-بروبيونيل لمساعد شيرال اشتقّت من سيس كحول التيربين - مايرتانول مع بينزالديهيد
 
Subject : Asymmertic aldol reactions of an N-propionyl dervative of chiral auxiliary derived from terpene alcohol cis- myrtanol with benzaldehyed 
Document Language : English 
Abstract : The asymmetric aldol reaction was carried out by deprotonating an N-propionyl derivative of alcohol-derived terpene "cis-myrtanol", chiral auxiliary with lithium diisopropylamide (LDA), and then treating the Z-lithium enolate with benzaldehyde. Unfortunately, analysis of 1H NMR spectrum of the crude aldol product showed poor diastereoselectivity. The boron enolate methodology was adopted to improve it. The boron enolate was generated by treatment of the N-propionyl derivative with Bu2BOTf and diisopropylethylamine and then treated with benzaldehyde. Analysis of 1H NMR spectrum of the crude aldol product obtained revealed an excellent diastereoselectivity. 
ISSN : 1012-1319 
Journal Name : Science Journal 
Volume : 20 
Issue Number : 1 
Publishing Year : 1423 AH
2003 AD 
Article Type : Article 
Added Date : Monday, February 21, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
طارق سبحيSobahi, Tariq ResearcherDoctorate 

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