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Document Type |
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Article In Journal |
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Document Title |
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Steroid-sensitive nephrotic syndrome and juvenile idiopathic arthritis بحث عن حاله طفله مصابه بالمتلازمة الكلوية ومرض الروماتزم |
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Subject |
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Steroid-sensitive nephrotic syndrome and juvenile idiopathic arthritis |
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Document Language |
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English |
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Abstract |
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Secondary nephrotic syndrome (NS) and kidney involve-ment are common in adults with rheumatoid arthritis (RA). Nephropathy in patients with RA varies and could be due to RA itself and/or to anti-rheumatic therapy [1]. Renal involvement usually occurs several years after the diagnosis of RA [2] and can present asglomeruloneph¬ritis (mesangial, membranous, focal proliferative. and minimal change lesions), amyloidosis. or interstitial ne¬phritis [I, 2]. Similarly, NS may complicate juvenile idiopathic arthritis (JIA) and has been described in adults [3], children [4J, and infants [5J with JlA. In these pa¬tients, it has been characterized by amyloidosis [3. 4, 5] and glomerulonephritis [61.
We report a case of primary steroid-sensitive NS (SSNS) and JIA in which nephrosis preceded the devel¬opment ofJIA by years. A 2.5-year-old Serlankian girl presented to King Abdul Aziz University Hospital with SSNS. She responded to steroid therapy, but demonstrat¬ed a frequently relapsing NS. She was maintained on low doses of alternate-day prednisolone to prevent relapses of NS. Four years later, at the age of 6.5 years. she pre¬sented withmonoarticular arthritis in the knee joint. She had left knee effusion that lasted for more than 6 months. Slit-lamp examination of her eyes revealed no abnormal¬ities. At presentation of her arthritis, her erythrocyte sed¬imentation rate was elevated at 96 mm/h, her comple¬ment levels were normal, and anti-nuclear antibody and |
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ISSN |
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1319-0989 |
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Journal Name |
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Arts and Humanities Journal |
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Volume |
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11 |
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Issue Number |
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17 |
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Publishing Year |
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1422 AH
2002 AD |
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Article Type |
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Article |
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Added Date |
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Monday, February 7, 2011 |
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Researchers
| جميلة قاري | Kari, jameela | Researcher | Doctorate | |
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